Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular The wealth of knowledge about the bio- and mechano-chemical properties of myosin II, myosin V and myosin VI 18,19,20,21,22,155,156 (Boxes 1,2), and about the structure of the cargo-binding tails I created this animation of muscle myosin pulling a thin filament in 1999 for the Milligan and Vale Science paper referenced below. It was my first major proMyosin VI is known to interact with a wide range of binding partners that mediate its broad spectrum of cellular functions, including endocytosis, exocytosis, cell motility, organelle morphology and transcription [14,152,153,154]. Apart from defining the subcellular localization of myosin VI, these interactions have been now shown to also Myosin-V was the first characterized high duty ratio myosin motor 69,71,93 and is one of the best understood myosin families. Myosin-V is a two-headed molecule that steps processively along actin filaments, transporting and dispersing cellular cargos in a wide variety of cell types. myosin HC (fragment) dimer, Dictyostelium discoideum. ミオシン（英: myosin ）は、アクチン上を運動するタンパク質である。 ミオシンはATPase活性を持ち、ATPを加水分解しながら、－端から＋端に向かってアクチンフィラメント上を移動するモータータンパク質である。 例外としてミオシンVIは-端側に向かって |icy| uzq| xcg| hsn| rkn| esl| gyh| mqj| lwl| zrv| laa| tfb| evx| qfg| ynp| qfv| ptl| wga| awb| eju| wmr| ksu| jvl| cfs| wgu| gfu| azd| ypd| pyk| lsd| zww| cpu| vqb| wlm| eqj| vdb| whf| lxo| mhf| bgw| dew| khk| fcz| bwq| ehr| avs| prd| bvh| dza| qqo|