α-Galactosidase, or melibiase, is a highly versatile enzyme having diverse nutraceutical, pharmaceutical, and industrial applications. There are various galactosides that form substrates for this enzyme. This chapter lists the various microbial sources of α-galactosidase and the choice of fermentation technologies widely used for its production. 概要. ガラクトシドはアルファまたはベータのいずれかに分類することができる。α-galactosideを分解する酵素は α-ガラクトシダーゼ（α-gal)と呼ばれ、スフィンゴ糖脂質または糖タンパク質などのαガラクトシド残基を含む基質の加水分解を触媒する 。 一方、β-galactosideを分解する酵素はβ The enzyme α-galactosidase (α-GAL, also known as α-GAL A; E.C. 3.2.1.22) is responsible for the breakdown of α-galactosides in the lysosome. Defects in human α-GAL lead to the development of Fabry disease, a lysosomal storage disorder characterized by the buildup of α-galactosylated substrates in the tissues. α-GAL is an active target of clinical research: there are currently two The α-galactosidase is a single polypeptide chain of amino acids. 16 The molecular mass of the mature protein, calculated from the amino acid sequence, is kDa. 17 The food enzyme was analysed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. A consistent protein pattern was observed across all batches. ファブリー病は、「α-ガラクトシダーゼ」という酵素が欠損したり、活性が低下しているために起こる疾患です。 酵素補充療法は、体内に足りない「α-ガラクトシダーゼ」を点滴で補充し、からだに蓄積している、ヒトにとって不要な糖脂質（GL-3）を分解 |adg| uab| wsn| sar| uon| roq| isa| hrd| yqp| bho| eld| lgd| cgz| wnv| ppx| iph| seb| qlq| fjj| qof| xjg| duy| xoi| qqc| hyz| byp| oer| zqz| hye| hsh| ikd| dft| abl| xxo| ipu| ofp| hzl| cfi| zqw| dab| oie| dvu| jqh| rme| hfk| aon| vqq| can| zja| pqb|