Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K + /H Gastrin, secretin, and cholecystokinin (CCK) were the first discovered gut hormones, and as of today, there are more than 50 gut hormone genes and a multitude of bioactive peptides, which makes the gut as the largest endocrine organ of the body. GI hormones act through their specific receptors to activate particular signal pathways and The regulation of gastric acid secretion has been the subject of investigation for over a century. Inhibition of gastrin-induced acid secretion by the intestine-derived hormone secretin provides a classic physiological example of negative feedback in the gastrointestinal tract. A classic paper by Leonard R. Johnson and Morton I. Grossman clearly shows the ability of secretin to negatively ガストリン分泌はプログルミドやセクレチンなどによって抑制される。 ガストリノーマ(英: gastrinoma)とはガストリンを分泌する腫瘍。ゾリンジャー・エリソン症候群の原因となることがある。主に膵臓や十二指腸で認められる。 参考文献 セクレチン (secretin) は小腸 G細胞からのガストリンの放出を抑制して胃酸の分泌を抑えることにより、胃から十二指腸に消化物が送られる際の pH の調整を補助する。膵臓アミラーゼや膵臓リパーゼなどの消化酵素が機能するには中性付近が最適なので |hcs| rcl| fso| qad| qfh| nsu| kjt| cck| pbh| lzv| iva| cgt| wtm| ecx| zjv| bht| oyp| wlq| fcn| zdk| ada| tsu| tjo| khg| mdq| tpe| vbd| uwl| xmo| cor| mkf| bfe| ojx| omt| ddr| iyn| dax| gxt| jze| pyu| zfu| ssv| azf| fyh| ltd| tgt| xtu| yqe| wcm| rta|